Dendritic Cells (DCs)-Based Cancer Immunotherapy: A Review on the Prospects of Medicinal Plants and Their Phytochemicals as Potential Pharmacological Modulators

Dendritic cells (DCs) are specialized antigen-presenting in humans and animals that provide antigen-specific T-cell immunity the body. It also establishes a linkage between innate adaptive immune responses. Various studies have shown malignancies or cancer may impair DCs effector functions. now become new molecular target for treatment of cancer. Modified matured could be novel biological modifiers to treat various diseases, including This review aims an update on impacts plant materials their phytochemicals DC-based immunotherapy. Existing literature immunotherapy plant-based pharmacological modulators has been explored over last decade using online databases such as Google Scholar, PubMed, Science Direct, Scopus. Mounting evidence from preclinical clinical findings suggests plants bioactive effective modulating system signaling pathways involved anti-tumor immunity. Despite prospective role herbs immunotherapy, most limited by either models crude extracts. provides useful perspective developing potential plant-derived